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Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus

Although antidiabetic agents have been developed to target one or more of the core defects of type 2 diabetes mellitus (T2DM), many patients do not achieve glycemic goals. Inhibition of the sodium-glucose cotransporter 2 (SGLT2) induces glycosuria, reduces glucose toxicity and improves insulin sensi...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Fioretto, Paola, Giaccari, Andrea, Sesti, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609166/
https://ncbi.nlm.nih.gov/pubmed/26474563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0297-x
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