A genome-wide approach to link genotype to clinical outcome by utilizing next generation sequencing and gene chip data of 6,697 breast cancer patients

BACKGROUND: The use of somatic mutations for predicting clinical outcome is difficult because a mutation can indirectly influence the function of many genes, and also because clinical follow-up is sparse in the relatively young next generation sequencing (NGS) databanks. Here we approach this proble...

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Publicado en:Genome Med
Autores principales: Pongor, Lőrinc, Kormos, Máté, Hatzis, Christos, Pusztai, Lajos, Szabó, András, Győrffy, Balázs
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609150/
https://ncbi.nlm.nih.gov/pubmed/26474971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0228-1
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