CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer

BACKGROUND: Induction chemotherapy incorporating docetaxel, cisplatin and 5- fluorouracil before radiotherapy may improve the outcome of patients with advanced head and neck cancer. Nevertheless, the addition of docetaxel increases hematological toxicity and infectious complications. Therefore, gene...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Melchardt, Thomas, Hufnagl, Clemens, Magnes, Teresa, Weiss, Lukas, Hutarew, Georg, Neureiter, Daniel, Schlattau, Alexander, Moser, Gerhard, Gaggl, Alexander, Tränkenschuh, Wolfgang, Greil, Richard, Egle, Alexander
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609094/
https://ncbi.nlm.nih.gov/pubmed/26475344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1776-x
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