Hippocampal proton MR spectroscopy as a novel approach in the assessment of radiation injury and the correlation to neurocognitive function impairment: initial experiences

BACKGROUND: The hippocampus is considered as the main radiosensitive brain structure responsible for postradiotherapy cognitive decline. We prospectively assessed correlation of memory change to hippocampal N-acetylaspartate (h-tNAA) concentration, a neuronal density and viability marker, by (1)H-MR...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Pospisil, Petr, Kazda, Tomas, Bulik, Martin, Dobiaskova, Marie, Burkon, Petr, Hynkova, Ludmila, Slampa, Pavel, Jancalek, Radim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609038/
https://ncbi.nlm.nih.gov/pubmed/26474857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0518-1
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