Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

The malaria parasite Plasmodium falciparum replicates within erythrocytes, producing progeny merozoites that are released from infected cells via a poorly understood process called egress. The most abundant merozoite surface protein, MSP1, is synthesized as a large precursor that undergoes proteolyt...

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Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Das, Sujaan, Hertrich, Nadine, Perrin, Abigail J., Withers-Martinez, Chrislaine, Collins, Christine R., Jones, Matthew L., Watermeyer, Jean M., Fobes, Elmar T., Martin, Stephen R., Saibil, Helen R., Wright, Gavin J., Treeck, Moritz, Epp, Christian, Blackman, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608996/
https://ncbi.nlm.nih.gov/pubmed/26468747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.09.007
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