Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1) / Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele

The Atypical ChemoKine Receptor 1 (ACKR1) gene, better known as Duffy Antigen Receptor for Chemokines (DARC or Duffy), is responsible for the Duffy Blood Group and plays a major role in regulating the circulating homeostatic levels of pro-inflammatory chemokines. Previous studies have shown that one...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Davis, Melissa B., Walens, Andrea, Hire, Rupali, Mumin, Kauthar, Brown, Andrea M., Ford, DeJuana, Howerth, Elizabeth W., Monteil, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608815/
https://ncbi.nlm.nih.gov/pubmed/26473357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140098
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