Naturally Occurring Deletion Mutants of the Pig-Specific, Intestinal Crypt Epithelial Cell Protein CLCA4b without Apparent Phenotype

The human CLCA4 (chloride channel regulator, calcium-activated) modulates the intestinal phenotype of cystic fibrosis (CF) patients via an as yet unknown pathway. With the generation of new porcine CF models, species-specific differences between human modifiers of CF and their porcine orthologs are...

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Опубликовано в: :PLoS One
Главные авторы: Plog, Stephanie, Klymiuk, Nikolai, Binder, Stefanie, Van Hook, Matthew J., Thoreson, Wallace B., Gruber, Achim D., Mundhenk, Lars
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608703/
https://ncbi.nlm.nih.gov/pubmed/26474299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140050
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