Aging Impairs the Ability of Conventional Dendritic Cells to Cross-Prime CD8(+) T Cells upon Stimulation with a TLR7 Ligand

The aging process is accompanied by altered immune system functioning and an increased risk of infection. Dendritic cells (DCs) are antigen-presenting cells that play a key role in both adaptive and innate immunity, but how aging affects DCs and their influence on immunity has not been thoroughly es...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zacca, Estefanía R., Crespo, María I., Acland, Rachel P., Roselli, Emiliano, Núñez, Nicolás G., Maccioni, Mariana, Maletto, Belkys A., Pistoresi-Palencia, María C., Morón, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608578/
https://ncbi.nlm.nih.gov/pubmed/26474053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140672
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