High-Dose Vitamin D and Calcium Attenuates Bone Loss with Antiretroviral Therapy Initiation: A Prospective, Randomized Placebo-Controlled Trial for Bone Health in HIV-Infected Individuals

BACKGROUND: Antiretroviral therapy (ART) initiation for HIV-1 infection is associated with 2-6% loss in bone mineral density (BMD). OBJECTIVE: To evaluate vitamin D3 (4000 IU daily) plus calcium (1000 mg calcium carbonate daily) supplementation on bone loss associated with ART initiation. DESIGN: 48...

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Publié dans:Ann Intern Med
Auteurs principaux: Overton, Edgar Turner, Chan, Ellen S., Brown, Todd T., Tebas, Pablo, McComsey, Grace A., Melbourne, Kathleen M., Napoli, Andrew, Hardin, William Royce, Ribaudo, Heather J., Yin, Michael T.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608553/
https://ncbi.nlm.nih.gov/pubmed/26075752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M14-1409
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