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Messenger RNA encoding constitutively active Toll-like receptor 4 enhances effector functions of human T cells
Adoptive T cell therapy of cancer employs a large number of ex-vivo-propagated T cells which recognize their targets either by virtue of their endogenous T cell receptor (TCR) or via genetic reprogramming. However, both cell-extrinsic and intrinsic mechanisms often diminish the in-vivo potency of th...
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| 出版年: | Clin Exp Immunol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley & Sons, Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608512/ https://ncbi.nlm.nih.gov/pubmed/26212048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12688 |
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