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Neurobehavioural abnormalities induced by repeated exposure of neonatal rats to sevoflurane can be aggravated by social isolation and enrichment deprivation initiated after exposure to the anaesthetic
BACKGROUND: We tested the hypothesis that developmental effects of repeated neonatal exposure to sevoflurane in rats are exacerbated by stressful experiences received later in life. METHODS: Sprague-Dawley male rats received sequential exposures to 3% sevoflurane for two h on postnatal days (P) six,...
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發表在: | Br J Anaesth |
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Main Authors: | , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Oxford University Press
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608490/ https://ncbi.nlm.nih.gov/pubmed/26475803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aev339 |
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