Genetics of systemic sclerosis: recent advances

PURPOSE OF REVIEW: Large-scale and follow-up genetic association studies in systemic sclerosis (SSc) have implicated over 40 regions in disease risk, 15 of which with robust associations. Nevertheless, the causal variants and the functional mechanisms underlying the genetic associations remain elusi...

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Bibliographic Details
Published in:Curr Opin Rheumatol
Main Authors: Ramos, Paula S., Silver, Richard M., Feghali-Bostwick, Carol A.
Format: Artigo
Language:Inglês
Published: Lippincott Williams And Wilkins 2015
Subjects:
RAYNAUD PHENOMENON, SCLERODERMA, OVERLAP SYNDROMES AND OTHER FIBROSING SYNDROMES: Edited by John Varga
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608482/
https://ncbi.nlm.nih.gov/pubmed/26317679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000214
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