Genetic Risk, Coronary Heart Disease Events, and the Clinical Benefit of Statin Therapy

BACKGROUND: Genetic variants have been associated with the risk of coronary heart disease (CHD). We tested whether a composite of these variants could identify the risk of both incident as well as recurrent CHD events and distinguish individuals who derived greater clinical benefit from statin thera...

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Pubblicato in:Lancet
Autori principali: Mega, JL, Stitziel, NO, Smith, JG, Chasman, DI, Caulfield, M, Devlin, JJ, Nordio, F, Hyde, C, Cannon, CP, Sacks, F, Poulter, N, Sever, P, Ridker, PM, Braunwald, E, Melander, O, Kathiresan, S, Sabatine, MS
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608367/
https://ncbi.nlm.nih.gov/pubmed/25748612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(14)61730-X
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