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Reversible activation of pH-sensitive cell penetrating peptides attached to gold surfaces()

pH-sensitive viral fusion protein mimics are widely touted as a promising route towards site-specific delivery of therapeutic compounds across lipid membranes. Here, we demonstrate that a fusion protein mimic, designed to achieve a reversible, pH-driven helix-coil transition mechanism, retains its f...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Baio, Joe E., Schach, Denise, Fuchs, Adrian V., Schmüser, Lars, Billecke, Nils, Bubeck, Christoph, Landfester, Katharina, Bonn, Mischa, Bruns, Michael, Weiss, Clemens K., Weidner, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608256/
https://ncbi.nlm.nih.gov/pubmed/25329926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc07278b
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