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Simultaneous Determinations of 17 marker compoundsin Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its Pharmacokinetic Studies in Mice

The purpose of this study is to develop and validate an UPLC-MS/MS method to quantify different marker compounds from Xiao-Chai-Hu-Tang (XCHT, a Chinese traditional herbal) in biological samples and apply the method to pharmacokinetic study. A Waters BEH C(18)UPLC column was used with acetonitrile/0...

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Détails bibliographiques
Publié dans:J Chromatogr B Analyt Technol Biomed Life Sci
Auteurs principaux: Sun, Rongjin, Zeng, Min, Du, Ting, Li, Li, Yang, Guangyi, Hu, Ming, Gao, Song
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608253/
https://ncbi.nlm.nih.gov/pubmed/26397748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2015.09.004
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