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Antigenically Modified Human Pluripotent Stem Cells Generate Antigen-Presenting Dendritic Cells
Human pluripotent stem cells (hPSCs) provide a promising platform to produce dendritic cell (DC) vaccine. To streamline the production process, we investigated a unique antigen-loading strategy that suits this novel platform. Specifically, we stably modified hPSCs using tumour antigen genes in the f...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608011/ https://ncbi.nlm.nih.gov/pubmed/26471005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15262 |
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