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Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson’s Disease: Environmental and Genetic Evidence

Movement abnormalities caused by chronic manganese (Mn) intoxication clinically resemble but are not identical to those in idiopathic Parkinson’s disease. In fact, the most successful parkinsonian drug treatment, the dopamine precursor levodopa, is ineffective in alleviating Mn-induced motor symptom...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Guilarte, Tomás R., Gonzales, Kalynda K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607750/
https://ncbi.nlm.nih.gov/pubmed/26220508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv099
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