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Cyclic Ozone Exposure Induces Gender-Dependent Neuropathology and Memory Decline in an Animal Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a major cause of dementia in the elderly. Although early-onset (familial) AD is attributed to gene mutations, the cause for late-onset (sporadic) AD, which accounts for 95% of AD cases, is unknown. In this study, we show that exposure of 6-week-old amyloid beta precursor...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Akhter, Hasina, Ballinger, Carol, Liu, Nianjun, van Groen, Thomas, Postlethwait, Edward M., Liu, Rui-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607745/
https://ncbi.nlm.nih.gov/pubmed/26116027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv124
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