Increased ribosomal accuracy increases a programmed translational frameshift in Escherichia coli.
We have tested the effect of increased ribosomal fidelity on a modified version of the programmed release factor 2 (RF2) translational frameshift. In the constructs tested, the original UGA codon at the site of the shift was replaced by either of two sense codons, UGG (tryptophan), which allows a fr...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8460140/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2315 |
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