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Pathogenic Transdifferentiation of Th17 Cells Contribute to Perpetuation of Rheumatoid Arthritis during Anti-TNF Treatment

T-helper cells producing interleukin (IL)-17A and IL-17F cytokines (Th17 cells) are considered the source of autoimmunity in rheumatoid arthritis (RA). In this study, we characterized specific pathogenic features of Th17 cells in RA. By using nano-string technology, we analyzed transcription of 419...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Andersson, Karin M E, Cavallini, Nicola Filluelo, Hu, Dan, Brisslert, Mikael, Cialic, Ron, Valadi, Hadi, Erlandsson, Malin C, Silfverswärd, Sofia, Pullerits, Rille, Kuchroo, Vijay K, Weiner, Howard L, Bokarewa, Maria I
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607618/
https://ncbi.nlm.nih.gov/pubmed/26062018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00057
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