Aspirin’s Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses

Salicylic acid (SA) and its derivatives have been used for millennia to reduce pain, fever and inflammation. In addition, prophylactic use of acetylsalicylic acid, commonly known as aspirin, reduces the risk of heart attack, stroke and certain cancers. Because aspirin is rapidly de-acetylated by est...

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Publicat a:Mol Med
Autors principals: Choi, Hyong Woo, Tian, Miaoying, Song, Fei, Venereau, Emilie, Preti, Alessandro, Park, Sang-Wook, Hamilton, Keith, Swapna, G V T, Manohar, Murli, Moreau, Magali, Agresti, Alessandra, Gorzanelli, Andrea, De Marchis, Francesco, Wang, Huang, Antonyak, Marc, Micikas, Robert J, Gentile, Daniel R, Cerione, Richard A, Schroeder, Frank C, Montelione, Gaetano T, Bianchi, Marco E, Klessig, Daniel F
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607614/
https://ncbi.nlm.nih.gov/pubmed/26101955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00148
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