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Fixed-Dose Combination Drug Approvals, Patents and Market Exclusivities Compared to Single Active Ingredient Pharmaceuticals

INTRODUCTION: Fixed-dose combinations (FDC) contain two or more active ingredients. The effective patent and exclusivity life of FDC compared to single active ingredient has not been assessed. OBJECTIVES: Trends in FDA approved FDC in the period 1980–2012 and time lag between approval of FDC and sin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hao, Jing, Rodriguez-Monguio, Rosa, Seoane-Vazquez, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607470/
https://ncbi.nlm.nih.gov/pubmed/26469277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140708
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