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Gedunin and Azadiradione: Human Pancreatic Alpha-Amylase Inhibiting Limonoids from Neem (Azadirachta indica) as Anti-Diabetic Agents

Human pancreatic α-amylase (HPA) inhibitors offer an effective strategy to lower postprandial hyperglycemia via control of starch breakdown. Limonoids from Azadirachta indica known for their therapeutic potential were screened for pancreatic α-amylase inhibition, a known anti-diabetic target. Studie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Ponnusamy, Sudha, Haldar, Saikat, Mulani, Fayaj, Zinjarde, Smita, Thulasiram, Hirekodathakallu, RaviKumar, Ameeta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607367/
https://ncbi.nlm.nih.gov/pubmed/26469405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140113
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