MYC and Human Telomerase Gene (TERC) Copy Number Gain in Early-stage Non–small Cell Lung Cancer

OBJECTIVES: We investigated the frequency of MYC and TERC increased gene copy number (GCN) in early-stage non–small cell lung cancer (NSCLC) and evaluated the correlation of these genomic imbalances with clinicopathologic parameters and outcome. MATERIALS AND METHODS: Tumor tissues were obtained fro...

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Veröffentlicht in:Am J Clin Oncol
Hauptverfasser: Flacco, Antonella, Ludovini, Vienna, Bianconi, Fortunato, Ragusa, Mark, Bellezza, Guido, Tofanetti, Francesca R., Pistola, Lorenza, Siggillino, Annamaria, Vannucci, Jacopo, Cagini, Lucio, Sidoni, Angelo, Puma, Francesco, Varella-Garcia, Marileila, Crinò, Lucio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607281/
https://ncbi.nlm.nih.gov/pubmed/25806711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COC.0000000000000012
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