Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2′-deoxycytidine

T cell immune dysfunction has an important role in the profound immunosupression that characterizes chronic lymphocytic leukemia (CLL). Improper polarization of T cells has been proposed as one of the mechanism involved. Mounting data implicates chromatin regulation, namely promoter methylation, in...

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Udgivet i:Leuk Res
Main Authors: Dubovsky, Jason A., Powers, John J., Gao, Yang, Mariusso, Luis F., Sotomayor, Eduardo M., Pinilla-Ibarz, Javier A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607255/
https://ncbi.nlm.nih.gov/pubmed/21377729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.02.007
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