Multicenter Phase II study of FOLFOX or biweekly XELOX and Erbitux (cetuximab) as first-line therapy in patients with wild-type KRAS/BRAF metastatic colorectal cancer: The FLEET study

BACKGROUND: The clinical benefit of cetuximab combined with oxaliplatin-based chemotherapy remains under debate. The aim of the present multicenter open-label Phase II study was to explore the efficacy and safety of biweekly administration of cetuximab and mFOLFOX-6 or XELOX as first-line chemothera...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Soda, Hitoshi, Maeda, Hiromichi, Hasegawa, Junichi, Takahashi, Takao, Hazama, Shoichi, Fukunaga, Mutsumi, Kono, Emiko, Kotaka, Masahito, Sakamoto, Junichi, Nagata, Naoki, Oba, Koji, Mishima, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607014/
https://ncbi.nlm.nih.gov/pubmed/26467662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1685-z
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