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Everolimus restrains the paracrine pro-osteoclast activity of breast cancer cells
BACKGROUND: Breast cancer (BC) cells secrete soluble factors that accelerate osteoclast (OC) differentiation, leading to the formation of osteolytic bone metastases. In the BOLERO-2 trial, BC patients with bone involvement who received Everolimus had a delayed tumor progression in the skeleton as a...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606500/ https://ncbi.nlm.nih.gov/pubmed/26468083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1717-8 |
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