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Systematic Analysis of the Associations between Adverse Drug Reactions and Pathways

Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic dat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Chen, Xiaowen, Wang, Yanqiu, Wang, Pingping, Lian, Baofeng, Li, Chunquan, Wang, Jing, Li, Xia, Jiang, Wei
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606217/
https://ncbi.nlm.nih.gov/pubmed/26495310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/670949
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