Co-Positivity for Anti-dsDNA, -Nucleosome and -Histone Antibodies in Lupus Nephritis Is Indicative of High Serum Levels and Severe Nephropathy

OBJECTIVE: To characterize the significance of correlated autoantibodies in systemic lupus erythematosus (SLE) and its complication lupus nephritis (LN) in a large cohort of patients. METHODS: Clinical data were statistically analyzed in 1699 SLE patients with or without nephritis who were diagnosed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yang, Jinfeng, Xu, Zhaozhen, Sui, Manshu, Han, Jihua, Sun, Lijie, Jia, Xiuzhi, Zhang, Haiyu, Han, Changsong, Jin, Xiaoming, Gao, Fei, Liu, Yanhong, Li, Yang, Cao, Jianbin, Ling, Hong, Zhang, Fengmin, Ren, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605492/
https://ncbi.nlm.nih.gov/pubmed/26465327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140441
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