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Cell type-selective disease-association of genes under high regulatory load
We previously showed that disease-linked metabolic genes are often under combinatorial regulation. Using the genome-wide ChIP-Seq binding profiles for 93 transcription factors in nine different cell lines, we show that genes under high regulatory load are significantly enriched for disease-associati...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605313/ https://ncbi.nlm.nih.gov/pubmed/26338775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv863 |
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