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Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM.

B lymphocytes from patients with X chromosome-linked immunoglobulin deficiency with normal or elevated serum IgM are unable to switch from the synthesis of IgM/IgD to that of other immunoglobulin isotypes. Isotype switch recombination was evaluated in three affected males by examining interleukin 4-...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Fuleihan, R, Ramesh, N, Loh, R, Jabara, H, Rosen, R S, Chatila, T, Fu, S M, Stamenkovic, I, Geha, R S
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7681587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2170
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