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Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches

Mitochondrial disorders are a group of highly invalidating human conditions for which effective treatment is currently unavailable and characterized by faulty energy supply due to defective oxidative phosphorylation (OXPHOS). Given the complexity of mitochondrial genetics and biochemistry, mitochond...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Di Meo, Ivano, Lamperti, Costanza, Tiranti, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604682/
https://ncbi.nlm.nih.gov/pubmed/26194912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505040
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