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Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

The nuclear hormone receptors called PPARs (peroxisome proliferator-activated receptors alpha, beta, and gamma) regulate the peroxisomal beta-oxidation of fatty acids by induction of the acyl-CoA oxidase gene that encodes the rate-limiting enzyme of the pathway. Gel retardation and cotransfection as...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Keller, H, Dreyer, C, Medin, J, Mahfoudi, A, Ozato, K, Wahli, W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.6.2160
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