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Adeno-associated-virus-mediated transduction of the mammary gland enables sustained production of recombinant proteins in milk

Biopharming for the production of recombinant pharmaceutical proteins in the mammary gland of transgenic animals is an attractive but laborious alternative compared to mammalian cell fermentation. The disadvantage of the lengthy process of genetically modifying an entire animal could be circumvented...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wagner, Stefan, Thresher, Rosemary, Bland, Ross, Laible, Götz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604487/
https://ncbi.nlm.nih.gov/pubmed/26463440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15115
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