Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD

Although autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease, and is characterized by the formation of multiple fluid-filled cysts, which results in renal failure, early diagnosis and treatment of ADPKD have yet to be defined. Herein, we observed that the promoter region...

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Publicat a:Sci Rep
Autors principals: Mi Woo, Yu, Shin, Yubin, Hwang, Jung-Ah, Hwang, Young-Hwan, Lee, Sunyoung, Young Park, Eun, Kyung Kong, Hyun, Cho Park, Hayne, Lee, Yeon-Su, Hoon Park, Jong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604459/
https://ncbi.nlm.nih.gov/pubmed/26463459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15238
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