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Evidence for cooperative tandem binding of hnRNP C RRMs in mRNA processing

The human hnRNP C is a ubiquitous cellular protein involved in mRNA maturation. Recently, we have shown that this protein specifically recognizes uridine (U) pentamers through its single RNA recognition motif (RRM). However, a large fraction of natural RNA targets of hnRNP C consists of much longer...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA
Prif Awduron: Cieniková, Zuzana, Jayne, Sandrine, Damberger, Fred Franz, Allain, Frédéric Hai-Trieu, Maris, Christophe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604433/
https://ncbi.nlm.nih.gov/pubmed/26370582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052373.115
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