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Dual functions of Macpiwi1 in transposon silencing and stem cell maintenance in the flatworm Macrostomum lignano

PIWI proteins and piRNA pathways are essential for transposon silencing and some aspects of gene regulation during animal germline development. In contrast to most animal species, some flatworms also express PIWIs and piRNAs in somatic stem cells, where they are required for tissue renewal and regen...

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Bibliografiska uppgifter
I publikationen:RNA
Huvudupphovsmän: Zhou, Xin, Battistoni, Giorgia, El Demerdash, Osama, Gurtowski, James, Wunderer, Julia, Falciatori, Ilaria, Ladurner, Peter, Schatz, Michael C., Hannon, Gregory J., Wasik, Kaja A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604429/
https://ncbi.nlm.nih.gov/pubmed/26323280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052456.115
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