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Differential effects of ribosomal proteins and Mg(2+) ions on a conformational switch during 30S ribosome 5′-domain assembly

Ribosomal protein S4 nucleates assembly of the 30S ribosome 5′ and central domains, which is crucial for the survival of cells. Protein S4 changes the structure of its 16S rRNA binding site, passing through a non-native intermediate complex before forming native S4-rRNA contacts. Ensemble FRET was u...

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Detalles Bibliográficos
Publicado en:RNA
Main Authors: Abeysirigunawardena, Sanjaya C., Woodson, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604426/
https://ncbi.nlm.nih.gov/pubmed/26354770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.051292.115
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