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Differential effects of ribosomal proteins and Mg(2+) ions on a conformational switch during 30S ribosome 5′-domain assembly

Ribosomal protein S4 nucleates assembly of the 30S ribosome 5′ and central domains, which is crucial for the survival of cells. Protein S4 changes the structure of its 16S rRNA binding site, passing through a non-native intermediate complex before forming native S4-rRNA contacts. Ensemble FRET was u...

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Publicado en:RNA
Autores principales: Abeysirigunawardena, Sanjaya C., Woodson, Sarah A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604426/
https://ncbi.nlm.nih.gov/pubmed/26354770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.051292.115
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