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Guanabenz Repurposed as an Antiparasitic with Activity against Acute and Latent Toxoplasmosis

Toxoplasma gondii is a protozoan parasite that persists as a chronic infection. Toxoplasma evades immunity by forming tissue cysts, which reactivate to cause life-threatening disease during immune suppression. There is an urgent need to identify drugs capable of targeting these latent tissue cysts,...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Benmerzouga, Imaan, Checkley, Lisa A., Ferdig, Michael T., Arrizabalaga, Gustavo, Wek, Ronald C., Sullivan, William J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604420/
https://ncbi.nlm.nih.gov/pubmed/26303803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01683-15
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