Deregulated Expression of SRC, LYN and CKB Kinases by DNA Methylation and Its Potential Role in Gastric Cancer Invasiveness and Metastasis

Kinases are downstream modulators and effectors of several cellular signaling cascades and play key roles in the development of neoplastic disease. In this study, we aimed to evaluate SRC, LYN and CKB protein and mRNA expression, as well as their promoter methylation, in gastric cancer. We found ele...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Mello, Adriano Azevedo, Leal, Mariana Ferreira, Rey, Juan Antonio, Pinto, Giovanny Rebouças, Lamarão, Leticia Martins, Montenegro, Raquel Carvalho, Alves, Ana Paula Negreiros Nunes, Assumpção, Paulo Pimentel, Borges, Barbara do Nascimento, Smith, Marília Cardoso, Burbano, Rommel Rodriguez
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604160/
https://ncbi.nlm.nih.gov/pubmed/26460485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140492
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki