Patterned polymer matrix promotes stemness and cell-cell interaction of adult stem cells

BACKGROUND: The interaction of stem cells with their culture substrates is critical in controlling their fate and function. Declining stemness of adult-derived human mesenchymal stem cells (hMSCs) during in vitro expansion on tissue culture polystyrene (TCPS) severely limits their therapeutic effica...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Hofmeister, Lucas H., Costa, Lino, Balikov, Daniel A., Crowder, Spencer W., Terekhov, Alexander, Sung, Hak-Joon, Hofmeister, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603908/
https://ncbi.nlm.nih.gov/pubmed/26464581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-015-0016-x
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