Using an Adenosine Triphosphate Bioluminescent Assay to Determine Effective Antibiotic Combinations against Carbapenem-Resistant Gram Negative Bacteria within 24 Hours

BACKGROUND: Current in vitro combination testing methods involve enumeration by bacterial plating, which is labor-intensive and time-consuming. Measurement of bioluminescence, released when bacterial adenosine triphosphate binds to firefly luciferin-luciferase, has been proposed as a surrogate for b...

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Publicat a:PLoS One
Autors principals: Cai, Yiying, Leck, Hui, Lim, Tze Peng, Teo, Jocelyn, Lee, Winnie, Hsu, Li Yang, Koh, Tse Hsien, Tan, Thuan Tong, Tan, Thean-Yen, Kwa, Andrea Lay-Hoon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603788/
https://ncbi.nlm.nih.gov/pubmed/26460891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140446
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