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Comprehensive molecular portraits of invasive lobular breast cancer

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 ductal (IDC), and 88 mixed IDC/ILC. Besides E-cadherin loss, the best known ILC genetic hallmark, we identified muta...

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Pubblicato in:Cell
Autori principali: Ciriello, Giovanni, Gatza, Michael L., Beck, Andrew H., Wilkerson, Matthew D., Rhie, Suhn K., Pastore, Alessandro, Zhang, Hailei, McLellan, Michael, Yau, Christina, Kandoth, Cyriac, Bowlby, Reanne, Shen, Hui, Hayat, Sikander, Fieldhouse, Robert, Lester, Susan C., Tse, Gary M.K., Factor, Rachel E., Collins, Laura C., Allison, Kimberly H., Chen, Yunn-Yi, Jensen, Kristen, Johnson, Nicole B., Oesterreich, Steffi, Mills, Gordon B., Cherniack, Andrew D., Robertson, Gordon, Benz, Christopher, Sander, Chris, Laird, Peter W., Hoadley, Katherine A., King, Tari A., Perou, Charles M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603750/
https://ncbi.nlm.nih.gov/pubmed/26451490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.033
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