Comprehensive molecular portraits of invasive lobular breast cancer

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 ductal (IDC), and 88 mixed IDC/ILC. Besides E-cadherin loss, the best known ILC genetic hallmark, we identified muta...

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Veröffentlicht in:Cell
Hauptverfasser: Ciriello, Giovanni, Gatza, Michael L., Beck, Andrew H., Wilkerson, Matthew D., Rhie, Suhn K., Pastore, Alessandro, Zhang, Hailei, McLellan, Michael, Yau, Christina, Kandoth, Cyriac, Bowlby, Reanne, Shen, Hui, Hayat, Sikander, Fieldhouse, Robert, Lester, Susan C., Tse, Gary M.K., Factor, Rachel E., Collins, Laura C., Allison, Kimberly H., Chen, Yunn-Yi, Jensen, Kristen, Johnson, Nicole B., Oesterreich, Steffi, Mills, Gordon B., Cherniack, Andrew D., Robertson, Gordon, Benz, Christopher, Sander, Chris, Laird, Peter W., Hoadley, Katherine A., King, Tari A., Perou, Charles M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603750/
https://ncbi.nlm.nih.gov/pubmed/26451490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.033
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