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Reconstruction of composite regulator-target splicing networks from high-throughput transcriptome data

We present a computational framework tailored for the modeling of the complex, dynamic relationships that are encountered in splicing regulation. The starting point is whole-genome transcriptomic data from high-throughput array or sequencing methods that are used to quantify gene expression and alte...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Papasaikas, Panagiotis, Rao, Arvind, Huggins, Peter, Valcarcel, Juan, Lopez, A Javier
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603746/
https://ncbi.nlm.nih.gov/pubmed/26449793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S10-S7
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