Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis)

INTRODUCTION: To determine whether the PTPN22 (protein tyrosine phosphatase nonreceptor 22)/CSK (c-src tyrosine kinase) pathway is implicated in the susceptibility and clinical heterogeneity of Henoch-Schönlein purpura (HSP) in the largest series of Caucasian HSP patients ever assessed for genetic s...

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Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: López-Mejías, Raquel, Genre, Fernanda, Remuzgo-Martínez, Sara, Pérez, Belén Sevilla, Castañeda, Santos, Llorca, Javier, Ortego-Centeno, Norberto, Ubilla, Begoña, Mijares, Verónica, Pina, Trinitario, Calvo-Río, Vanesa, Palmou, Natalia, Miranda-Filloy, José A., Parejo, Antonio Navas, Argila, Diego, Sánchez-Pérez, Javier, Rubio, Esteban, Luque, Manuel León, Blanco-Madrigal, Juan María, Galíndez-Aguirregoikoa, Eva, Ocejo-Vinyals, J. Gonzalo, Martín, Javier, Blanco, Ricardo, González-Gay, Miguel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603645/
https://ncbi.nlm.nih.gov/pubmed/26458874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0796-x
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