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Reconstruction of an ancestral Yersinia pestis genome and comparison with an ancient sequence

BACKGROUND: We propose the computational reconstruction of a whole bacterial ancestral genome at the nucleotide scale, and its validation by a sequence of ancient DNA. This rare possibility is offered by an ancient sequence of the late middle ages plague agent. It has been hypothesized to be ancestr...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Duchemin, Wandrille, Daubin, Vincent, Tannier, Eric
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603589/
https://ncbi.nlm.nih.gov/pubmed/26450112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S10-S9
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