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Candida parapsilosis produces prostaglandins from exogenous arachidonic acid and OLE2 is not required for their synthesis

Prostaglandins are C20 fatty acid metabolites with diverse biological functions. In mammalian cells, prostaglandins are produced from arachidonic acid (AA) via cyclooxygenases (COX1 and COX2). Although fungi do not possess cyclooxygenase homologues, several pathogenic species are able to produce pro...

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Bibliographische Detailangaben
Veröffentlicht in:Virulence
Hauptverfasser: Grózer, Zsuzsanna, Tóth, Adél, Tóth, Renáta, Kecskeméti, Anita, Vágvölgyi, Csaba, Nosanchuk, Joshua D, Szekeres, András, Gácser, Attila
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603437/
https://ncbi.nlm.nih.gov/pubmed/25654274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.988097
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