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Click with a Boronic Acid Handle: A Neighboring Group-assisted Click Reaction that Allows Ready Secondary Functionalization

The feasibility of a neighboring boronic acid-facilitated facile condensation of an aldehyde is described. This reaction is bio-orthogonal, complete at room temperature within minutes, and suitable for bioconjugation chemistry. The boronic acid group serves the dual purpose of catalyzing the condens...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Draganov, Alexander B., Wang, Ke, Holmes, Jalisa, Damera, Krishna, Wang, Danzhu, Dai, Chaofeng, Wang, Binghe
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603419/
https://ncbi.nlm.nih.gov/pubmed/26327521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc05890b
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