Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease

OBJECTIVE: People with Parkinson disease (PD) frequently develop dementia, which is associated with neocortical deposition of alpha-synuclein (α-syn) in Lewy bodies and Lewy neurites. In addition, neuronal loss and deposition of aggregated α-syn also occur in multiple subcortical nuclei that project...

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Veröffentlicht in:Ann Clin Transl Neurol
Hauptverfasser: Buddhala, Chandana, Loftin, Susan K, Kuley, Brandon M, Cairns, Nigel J, Campbell, Meghan C, Perlmutter, Joel S, Kotzbauer, Paul T
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603378/
https://ncbi.nlm.nih.gov/pubmed/26478895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.246
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